碘同位素交换反应在碘吸附器性能评价应用中的可行性研究

辐射防护 ›› 2019, Vol. 39 ›› Issue (2): 124-129.

碘同位素交换反应在碘吸附器性能评价应用中的可行性研究

高琳锋, 姚岩岩², 王雷², 张渊¹, 赵高昕²

1.中国辐射防护研究院, 太原 030006;
2.阳江核电有限公司,广东阳江 529941

收稿日期:2018-06-07 出版日期:2019-03-20 发布日期:2019-11-08
作者简介:高琳锋(1985—),男,2008年毕业于山西大同大学应用化学专业,2011年毕业于西北工业大学凝聚态物理专业,获硕士学位,助理研究员。E-mail:gaolinfeng2008@126.com

Feasibility study on application of iodine isotope exchange reaction inperformance evaluation of iodine adsorbers

GAO Linfeng¹, YAO Yanyan², WANG Lei², ZHANG Yuan¹, ZHAO Gaoxin²

1.China Institute for Radiation Protection, Taiyuan 030006;
2.Yangjiang Nuclear Power Co., Ltd., Guangdong Yangjiang 529941

Received:2018-06-07 Online:2019-03-20 Published:2019-11-08

摘要/Abstract

摘要： 依据卤代烃亲核取代反应的特性,设计了碘同位素交换反应制备放射性甲基碘的实验方案。结合核电站现场安全管理要求,对实验试剂进行物性分析和毒理分析。通过实验进行了示踪剂验证、碘同位素交换验证、实验效率分析、实验安全性分析、试剂管理及放射性残液处理等方面的研究,初步验证了用碘同位素交换反应制备放射性甲基碘在碘吸附器性能评价应用中的可行性。

关键词: 同位素交换, 放射性甲基碘, 试剂管理, 安全控制

Abstract: An experimental scheme of iodine isotope exchange reaction for preparing radioactive methyl iodide is designed on the basis of characteristics of nucleophilic substitution reaction of halogenated hydrocarbon. According to safety management requirements of nuclear power plants, physical property analysis and toxicology analysis of experimental reagents are carried out. Tracer verification, iodine isotope exchange verification, experimental efficiency analysis, experimental safety analysis, reagent management method, and radioactive residue treatment were also studied for feasibility study of iodine isotope exchange reaction of radioactive methyl iodide preparation in performance evaluation of iodine adsorbers.

Key words: isotope exchange, radioactive methyl iodide, reagent management, safety control

中图分类号:

TL92+3

高琳锋, 姚岩岩, 王雷, 张渊, 赵高昕. 碘同位素交换反应在碘吸附器性能评价应用中的可行性研究[J]. 辐射防护, 2019, 39(2): 124-129.

GAO Linfeng, YAO Yanyan, WANG Lei, ZHANG Yuan, ZHAO Gaoxin. Feasibility study on application of iodine isotope exchange reaction inperformance evaluation of iodine adsorbers[J]. RADIATION PROTECTION, 2019, 39(2): 124-129.

参考文献

[1] 中国辐射防护研究院. 核空气净化系统碘吸附器净化系数的测定放射性甲基碘法:EJ/T 1183—2005[S]. 北京:中国核工业总公司,2005.
[2] AFNOR Standard. Nuclear Energy, Nuclear ventilation installation, Method of control of the scrubbing coefficient of iodine traps:NF M62-206[S]. France:AFNOR,1984.
[3] Eisenhut M. Simple labeling of ω-phenylfatty acids by iodine isotope exchange[J]. International Journal of Applied Radiation & Isotopes, 1982, 33(7):499-504.
[4] Gleason G I. Some notes on the exchange of iodine with thyroxine homologues.[J]. Journal of Biological Chemistry, 1955, 213(2):837.
[5] Bakker C N M, Kaspersen F M. The labeling of 4-alkylamino-iodoquinolines with radioactive iodine by isotopic exchange[J]. Journal of Labelled Compounds & Radiopharmaceuticals, 2010, 16(6):917-928.
[6] Millard P, Portais J C, Mendes P. Impact of kinetic isotope effects in isotopic studies of metabolic systems[J]. Bmc Systems Biology, 2015, 9(1):1-13.
[7] El-Shaboury G, Farah K, El-Bayoumy S. Isotope exchange of iodine between sodium iodide [Na ¹³¹ I] and [4-¹²⁷ I]iodoantipyrine via organic medium[J]. Journal of Radioanalytical & Nuclear Chemistry, 1991, 153(3):201-209.
[8] Juliusburger F, Topley B, Weiss J. Isotopic exchange reactions with iodine[J]. Journal of Chemical Physics, 1935, 3(7):437-438.
[9] Straaten H V D, Aten A H W. The Exchange of iodine between organic iodides and inorganic iodine in aqueous solution[J]. J Am Chem Soc, 1954, 76(14):3 798-3 800.
[10] Miller V B, Neiman M B, Solodovnikov S P. Isotopic exchange between methyl iodide and iodine[J]. Bulletin of the Academy of Sciences of the Ussr Division of Chemical Science, 1959, 8(2):227-230.
[11] Hodgson G W, Evans H G V, Winkler C A. The exchange of iodine between inorganic iodides and n -butyl iodide [J]. Canadian Journal of Chemistry, 1951, 29(29):60-69.
[12] 倪沛州. 有机化学:第6版[M]. 北京: 人民卫生出版社,2008:111-143.
[13] 邢其毅,裴伟伟,徐瑞秋,等. 基础有机化学:第3版[M]. 北京:高等教育出版社,2008:242-296.
[14] 王积涛,王永梅,张宝申,等. 有机化学:第3版[M].天津:南开大学出版社,2009:230-273.