吸入氡子体肺部有效剂量转换系数的影响因素研究

辐射防护 ›› 2023, Vol. 43 ›› Issue (1): 64-71.

吸入氡子体肺部有效剂量转换系数的影响因素研究

马天赐¹, 向东¹, 程卫亚², 谭至宇², 陈亮平²

1.南华大学核科学技术学院,湖南衡阳 421001;
2.中国原子能科学研究院,北京 102413

收稿日期:2022-05-24 出版日期:2023-01-20 发布日期:2023-03-20
作者简介:马天赐(1998—),男,2019年毕业于石家庄铁道大学电气工程及其自动化专业,现为南华大学核科学技术学院能源动力核能工程专业在读硕士研究生。E-mail:740844172@qq.com

Study on the influencing factors of pulmonary effective dose conversion coefficient of inhaled radon progeny

MA Tianci¹, XIANG Dong¹, CHENG Weiya², TAN Zhiyu², CHEN Liangping²

1. School of Nuclear Science and Technology,University of South China,Hunan Hengyang 421001;
2. China Institute of Atomic Energy, Beijing 102413

Received:2022-05-24 Online:2023-01-20 Published:2023-03-20

摘要/Abstract

摘要： 基于ICRP 66号报告中的呼吸道生物动力学模型,采用MATLAB软件中的Simulink仿真工具,建立了人体呼吸道的廓清模型,利用建立的廓清模型计算了不同参数条件下肺部有效剂量转换系数(mSv/WLM)的变化规律。结果显示吸入氡子体粒径对肺部有效剂量转换系数的影响最大,当粒径在0.7~10 000 nm之间变化时,肺部有效剂量转换系数的变化能达到10倍以上;其次是呼吸率,呼吸率直接决定了吸入氡子体粒子的数量,当成年男性重度工作状态时肺部有效剂量转换系数是睡眠状态下的4.2倍;未结合态份额对剂量转换系数的影响会随着吸入氡子体粒径值不同而发生改变,当未结合态份额从0变化到0.08时,肺部有效剂量转换系数最多能增大79%;相比而言吸收入血速率对肺部有效剂量转换系数的影响只有不到4%。

关键词: Simulink, 氡子体, 内照射, 呼吸道廓清模型

Abstract: Based on the respiratory tract biodynamic model in ICRP 66 report, this paper established the clearance model of human respiratory tract by using Simulink simulation tool in MATLAB software. The variation of pulmonary effective dose conversion coefficient (mSv/WLM) under different parameters was calculated by using the clearance model. The results showed that the particle size of inhaled radon progeny had the greatest influence on the lung effective dose conversion coefficient. The lung effective dose conversion coefficient could change more than 10 times when the particle size range was between 0.7 nm and 10,000 nm. The second factor is respiration rate, which directly determines the number of radon daughter particles inhaled. The lung effective dose conversion coefficient of a male under heavy working state is 4.2 times that of a male under sleep state. The effect of unbound state fraction on dose conversion coefficient will change with the size of inhaled radon daughters. When the unbound state fraction changes from 0 to 0.08, the lung effective dose conversion coefficient can increase by 79% at most. In contrast, absorbed blood rate only affects the pulmonary effective dose conversion coefficient by less than 4%.

Key words: simulink, radon progeny, internal irradiation, respiratory tract clearance model

中图分类号:

TL72

马天赐, 向东, 程卫亚, 谭至宇, 陈亮平. 吸入氡子体肺部有效剂量转换系数的影响因素研究[J]. 辐射防护, 2023, 43(1): 64-71.

MA Tianci, XIANG Dong, CHENG Weiya, TAN Zhiyu, CHEN Liangping. Study on the influencing factors of pulmonary effective dose conversion coefficient of inhaled radon progeny[J]. RADIATION PROTECTION, 2023, 43(1): 64-71.

参考文献

[1] Charles M. UNSCEAR Report 2000:sources and effects of ionizing radiation[J]. Journal of Radiological Protection,2001,21(1):83.
[2] Council N . Health Effects of Exposure to Radon: BEIR VI[J]. National Academies Press, 1999.
[3] 毕垒,尚兵,李玮博,等. 室内²²⁰Rn子体剂量转换因子研究动态与发展趋势[C]//第三次全国天然辐射照射与控制研讨会论文汇编.2010:660-664.
[4] 张磊,郭秋菊.气溶胶粒径分布对肺模型评价氡子体有效剂量的影响[J].核电子学与探测技术,2008,28(06):1203-1208.
[5] 张磊,郭秋菊,郭露,等.现场环境氡子体未结合态份额测量及剂量评价[J].辐射防护,2012,32(05):305-310.
[6] 赵桐可,郑平辉,阿不都莫明·卡地尔,等.氡子体比的现场测量及其对剂量转换系数的影响[J].原子能科学技术,2015,49(09):1705-1710.
[7] ICRP. Human respiratory tract model for radiological protection[R]. ICRP Publication 66. Oxford:Pergamon, 1994.
[8] 潘羽晞. 氡子体多尺度剂量学方法研究与应用[D].清华大学,2016.
[9] Jarvis N S,Birchall A,James A C,et al. LUDEP 2.0: Personal computer program for calculating internal doses using the ICRP Publication 66 respiratory tract model[J]. Chilton,UK:National Radiological Protection Board, 2010.
[10] 周永增.估算放射性核素所致内照射剂量的ICRP剂量学和生物动力学模型[J].辐射防护,1999,19(01):13-23.
[11] 袁炜烨,王一迪,席悦,等.呼吸道含铀化合物滞留廓清模型及单次吸入肺部滞留量计算[J].核技术,201,42(11):47-54.
[12] ICRP. Lung Cancer Risk from Radon and Progeny and Statement on Radon[R]. ICRP Publication 115. Oxford: Pergamon, 2010.
[13] 文德智. 基于matlab/simulink的ICRP生物动力学模型仿真方法[C]//中国职业安全健康协会2013年学术年会论文集. 2013:668-683.
[14] 成智威,申茂泉,杨文静,等.基于ICRP呼吸道新模型的胸区各库滞留函数的计算原子能科学技术[J].2015,49(07):1303-1308.
[15] Marsh J W,Birchall A,Birchall A. Sensitivity analysis of the weighted equivalent lung dose per unit exposure from radon progeny[J]. Radiation Protection Dosimetry,2000,87(3):169-170.
[16] Farkas Á,Balásházy I. Development and application of a complex numerical model and software for the computation of dose conversion factors for radon progenies[J]. Radiation Protection Dosimetry,2015,164(3):278-290.
[17] Piotr T,Wasiolek,Anthony C. James. Unattached fraction measuring technique and radon lung dose[J]. Journal of Environmental Radioactivity,2000,51(1):137-151.
[18] Paquet F, Bailey M R, Leggett R W, et al. ICRP publication 137: Occupational intakes of radionuclides: Part 3[R]. Annals of the ICRP, 2017, 46(3-4): 1-486.