基于体素模型的光子外照射大鼠器官剂量模拟计算

辐射防护 ›› 2020, Vol. 40 ›› Issue (6): 522-526.

基于体素模型的光子外照射大鼠器官剂量模拟计算

张晓敏, 李大伟, 宁静, 谢向东

军事科学院军事医学研究院,北京 100850

出版日期:2020-11-20 发布日期:2021-01-27
作者简介:张晓敏(1980—),男,2002年本科毕业于防化学院核技术与核安全专业,2010年博士毕业于军事科学院放射医学专业,副研究员。E-mail:amms_zhangxm@163.com

Rat organ dose calculation for external photon irradiation basedon voxel model based on voxel model

ZHANG Xiaomin, LI Dawei, NING Jing, XIE Xiangdong

Academy of Military Medical Sciences,Academy of Military Sciences,Beijing 100850

Online:2020-11-20 Published:2021-01-27

摘要/Abstract

摘要： 获得外照射条件下的大鼠器官剂量,对于放射医学剂量-效应关系研究具有重要意义。本文基于大鼠微型CT图像建立大鼠体素模型,并研究光子外照射情况下大鼠器官剂量。大鼠体素模型质量323.7 g,单个体素尺寸为0.16 mm×0.16 mm×2 mm,包含大鼠大部分关键器官和组织。利用蒙特卡罗模拟程序MCNP计算获得了4种照射几何条件、21个单能(10 keV～10 MeV)平行光子束外照射情况下的器官剂量转换系数,最后对器官剂量随光子能量的变化进行了分析与讨论。

关键词: 器官剂量, 体素模型, 蒙特卡罗模拟, 光子外照射

Abstract: To obtain the organ dose of externally exposed rat for studying dose-effect relationship in radiation medicine,a voxel model based on Micro-CT images of a SD rat was developed to calculate rat organ dose for external photon irradiation.The rat voxel model had a size of 0.16 mm×0.16 mm×2 mm,weighed about 323 g and contained most of the key organs or tissues.Monte Carlo simulation was carried out to obtain organ dose conversion coefficients for 21 external monoenergetic parallel photon beams between 10 keV and 10 MeV under four different irradiation geometry conditions.The organ dose with varying photon energy was also discussed and analyzed.

Key words: organ dose, voxel model, monte carlo simulation, external photon irradiation

中图分类号:

TL72

张晓敏, 李大伟, 宁静, 谢向东. 基于体素模型的光子外照射大鼠器官剂量模拟计算[J]. 辐射防护, 2020, 40(6): 522-526.

ZHANG Xiaomin, LI Dawei, NING Jing, XIE Xiangdong. Rat organ dose calculation for external photon irradiation basedon voxel model based on voxel model[J]. RADIATION PROTECTION, 2020, 40(6): 522-526.

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