BNCT束流参数测量多成像板探测器设计及优化

辐射防护 ›› 2025, Vol. 45 ›› Issue (6): 609-618.

BNCT束流参数测量多成像板探测器设计及优化

加德拉·库阿尼别克¹, 赵日¹, 李德源¹, 闫学文¹, 陈法国^1,2, 乔朝蓬¹, 张鹏鹏¹, 张可¹

1.中国辐射防护研究院,太原 030006;
2.核药研发转化与精准防护山西省重点实验室,太原 030006

收稿日期:2025-06-23 出版日期:2025-11-20 发布日期:2026-01-14
通讯作者: 李德源。E-mail:ldy21q21@126.com
作者简介:加德拉·库阿尼别克(1999—),女,2023年毕业于西安交通大学新能源科学与工程专业,获学士学位,现为中国辐射防护研究院环境科学专业在读硕士研究生。E-mail:jdjdr99@163.com
基金资助:
国家自然科学基金(12305402)。

Design and optimization of a multi-imaging plate detector for BNCT beam parameter measurement

JIADELA Kuanibieke¹, ZHAO Ri¹, LI Deyuan¹, YAN Xuewen¹, CHEN Faguo^1,2, QIAO Zhaopeng¹, ZHANG Pengpeng¹, ZHANG Ke¹

1. China Institute for Radiation Protection, Taiyuan 030006;
2. Shanxi Provincial Key Laboratory of Nuclear Drug and Transformation and Precision Protection, Taiyuan 030006

Received:2025-06-23 Online:2025-11-20 Published:2026-01-14

摘要/Abstract

摘要： 硼中子俘获治疗(boron neutron capture therapy,BNCT)束流质量是确保其疗效的重要因素。近年来,多成像板测量系统成为BNCT束流参数测量领域的研究热点。多成像板系统中,各转换层厚度是决定其测量准确性的关键参数。采用粒子群算法对转换层厚度进行优化设计,基于蒙特卡罗模拟方法计算每步迭代中系统探测响应矩阵,并选取该矩阵的条件数作为优化目标,通过大量迭代,最终得到各厚度的最优值。在此基础上,进一步对最优解进行物理机制分析,从次级带电粒子射程、转换层对各成像板增强效应等角度阐释了最优解的合理性。研究结果为开展BNCT束流参数测量多成像板系统开发提供了关键参考数据。

关键词: BNCT, 多成像板, 粒子群优化, 束流参数测量, 蒙特卡罗模拟

Abstract: The beam quality of Boron Neutron Capture Therapy (BNCT) is a crucial factor affecting its therapeutic efficacy. In recent years, multi-imaging plate systems have attracted increasing attention for measuring BNCT beam parameters. In such systems, the thickness of the conversion layers plays a key role in determining measurement accuracy. This study applies a particle swarm optimization algorithm to optimize the conversion layer thicknesses. A Monte Carlo simulation is used to calculate the system’s response matrix at each step of iteration. The condition number of the response matrix is chosen as the optimization objective. Through iterative computations, the optimal thickness values are obtained. Based on these results, a physical interpretation is further provided, focusing on the range of secondary charged particles and the enhancement effects of the conversion layers on each imaging plate. The research findings offer important reference data for the development of multi-imaging plate detectors for BNCT beam characterization.

Key words: BNCT, multi-imaging plate, particle swarm optimization, beam parameter measurement, Monte Carol simulation

中图分类号:

R144.1

加德拉·库阿尼别克, 赵日, 李德源, 闫学文, 陈法国, 乔朝蓬, 张鹏鹏, 张可. BNCT束流参数测量多成像板探测器设计及优化[J]. 辐射防护, 2025, 45(6): 609-618.

JIADELA Kuanibieke, ZHAO Ri, LI Deyuan, YAN Xuewen, CHEN Faguo, QIAO Zhaopeng, ZHANG Pengpeng, ZHANG Ke. Design and optimization of a multi-imaging plate detector for BNCT beam parameter measurement[J]. RADIATION PROTECTION, 2025, 45(6): 609-618.

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