电磁生物效应辐照和检测系统及其应用

辐射防护 ›› 2015, Vol. 35 ›› Issue (6): 373-380.

电磁生物效应辐照和检测系统及其应用

张杰, 王向晖, 齐红新, 陈树德, 乔登江

华东师范大学物理系,上海 200241

收稿日期:2014-12-23 出版日期:2015-11-20 发布日期:2024-10-22
通讯作者: 齐红新。E-mail:flyerqhx@126.com
作者简介:张杰(1981—),男, 2008年毕业于华东师范大学光学专业,获理学博士学位,工程师。E-mail:jzhang@phy.ecnu.edu.cn
基金资助:
国家973项目资助(项目编号:2011CB503701)。

Irradiating and detecting systems applied in bioelectromagnetic study and its applications

Zhang Jie, Wang Xianghui, Qi Hongxin, Chen Shude, Qiao Dengjiang

Physics Department of East China Normal University, Shanghai 200241

Received:2014-12-23 Online:2015-11-20 Published:2024-10-22

摘要/Abstract

摘要： 电磁波广泛应用于医疗、通讯等诸多领域,而且应用的频率和功率也在逐渐增大。电磁波对生物体的影响也受到人们的广泛关注,相关研究也在进行中。文献报道中电磁波辐照生物体的辐照条件(如极化方向、波矢方向等)不够详尽,作用于生物体内部的电磁照射量无法比较。本文详细报道了可用于辐照活体动物和离体细胞、蛋白质,长波到短波波段的电磁辐照系统和可用于测定电磁照射量的检测系统及其性能,简述了应用这些设备仪器已进行的电磁生物效应研究。这将为进一步研究电磁生物效应及其应用提供可靠的硬件支撑。

关键词: 电磁辐照, 电磁生物效应, 照射量

Abstract: Electromagnetic wave (EMW) was applied in medical, communication and so on. The frequency and power was becoming higher. Bioelectromagnetic effects had been paid abroad attentions and the study on bioeffect of EMW was under way. However, in many references, irradiating conditions, such as directions of polarization and wave vector, were not detailed so that irradiation dose in organism could not be compared, which is the main reason that the results is in conflict. In this paper, EMW devices from long wave to short wave and its characters were thoroughly introduced, which could be used to study bio-EMW effect of animal in vivo, cells and proteins. Its detecting devices were also presented. It would be benefit to the study of bio-EMW effects and its applications.

Key words: electromagnetic irradiation, bio-electromagnetic effect, irradiation dose

张杰, 王向晖, 齐红新, 陈树德, 乔登江. 电磁生物效应辐照和检测系统及其应用[J]. 辐射防护, 2015, 35(6): 373-380.

Zhang Jie, Wang Xianghui, Qi Hongxin, Chen Shude, Qiao Dengjiang. Irradiating and detecting systems applied in bioelectromagnetic study and its applications[J]. RADIATION PROTECTION, 2015, 35(6): 373-380.

参考文献

[1] Alessandra Paffi, Francesca Apollonio, Giorgio Alfonso Lovisolo, et al. Considerations for developing an RF exposure system: a review for in vitro biological experiments [J]. IEEE Transactions on Microwave Theory and Techniques, 2010, 58(10): 2 702-2 714.
[2] Igor Belyaev. Non-thermal biological effects of microwaves[J]. Microwave Review, 2005, 11(2): 13-29.
[3] Neils Kuster, Veronica Berdinas,Neviana Nikoloski, et al. Methodology of detailed dosimetry and treatment of uncertainty and variations for in vivo studies [J]. Bioelectromagnetics, 2006, 27: 378-391.
[4] Bakker JF, Paulides MM, Christ A,et al. Assessment of induced SAR in children exposed to electromagnetic plane waves between 10 MHz and 5.6 GHz [J]. Physics in Medicine and Biology, 2010, 55: 3 115-3 130.
[5] Siriwat Wasoontarajaroen, Artnarong Thansandote, Gregory B,et al. Dosimetry evaluation of a cylindrical waveguide chamber for unrestrained small rodents at 1.9 GHz [J]. Bioelectromagnetics, 2012, 33: 575-584.
[6] Jia Caili, Zhou Zhenjie, Liu Renchen, et al. EGF receptor clustering is induced by 0.4 mT power frequency magnetic field and blocked by the EGF receptor tyrosine kinase inhibitor PD153035[J]. Bioelectromagnetics, 2007, 28(3):197-207.
[7] Wu Xia, Cao Meiping, Shen Yunyun, et al. Weak power frequency magnetic field acting similarly to EGF stimulation induces acute activations of the EGFR sensitive actin cytoskeleton motility in human amniotic cells [J]. PLoS One, 2014, 9(2): e87626.
[8] 褚克平, 蔡知音, 张玉焜,等. 0.4 mT工频磁场对CHL细胞微丝装配的影响[J]. 中国辐射卫生, 2007, 16(3): 259-261.
[9] 褚克平, 蔡知音, 张丹英,等. 0.2 mT工频磁场引起人羊膜成纤维细胞微丝骨架重组[J]. 中国预防医学杂志, 2007, 41(5): 391-395.
[10] He YL, Liu DD, Fang YJ, et al. Exposure to extremely low frequency electromagnetic fields modulates Na⁺ currents in rat cerebellar granule cells through increase of AA/PGE2 and EP receptor mediated cAMP/PKA pathway[J]. PLoS One, 2013, 8(1): e54376.
[11] 田冰, 贾彩丽, 夏若虹,等. 50 Hz脉冲电场作用下胰岛素构象变化的拉曼光谱分析[J]. 光谱学与光谱分析, 2004, 24(11):1 331-1 333.
[12] 李乐军, 陈树德, 乔登江. 脉冲电场与牛血清白蛋白相互作用的同步荧光光谱和拉曼光谱比较研究[J]. 光谱学与光谱分析, 2006, 26(1): 81-85.
[13] 严喆, 陈树德, 乔登江. 温度与电磁参数协同影响胰岛素分子构象与功能的光谱学方法研究[J]. 光谱学与光谱分析, 2008, 28(6): 1 343-1 347.
[14] 叶红, 黄琳玲, 陈树德,等. 脉冲电场对悬浮中国红豆杉细胞的影响[J]. 华东师范大学(自然版), 2005, 2005(2): 58-64.
[15] 丁荔萍, 张红锋, 陈树德,等. 低频脉冲电场对胰岛素介导的细胞增殖影响及其作用机理研究[J]. 细胞生物学杂志, 2002, 24(5): 303-306.
[16] 裴剑, 黄欣, 陈树德,等. 9.33 GHz高功率脉冲微波对IAR20鼠肝细胞和L-02人肝细胞增殖的影响[J]. 强激光与粒子束, 2011, 23(11): 2 850-2 854.
[17] 裴剑, 黄欣, 陈树德,等. 高功率脉冲微波细胞生物效应中脉冲个数与效应的关系研究[J]. 辐射防护, 2012, 32(1): 1-7.
[18] 匡玉标. 脉冲微波辐照对大鼠海马影响的研究[D]. 上海:华东师范大学, 2011.
[19] 张杰, 韩黎军, 谢涛嵘,等. 8 mm波辐照鼠皮肤损伤观察及温升仿真[J]. 红外与毫米波学报, 2008, 27(1): 56-59.
[20] 张杰, 王立斌, 谢涛嵘,等. 高功率毫米波辐照鼠疼痛阈值及应激反应[J]. 强激光与粒子束,2007, 19(3): 439-442.
[21] 王立斌, 谢涛嵘, 程和平,等. 在高功率毫米波暴露下大鼠和小鼠的致伤和致死实验观察[J]. 辐射防护, 2006, 26(3): 166-171.
[22] 谢涛嵘, 裴剑, 陈超,等. 高功率毫米波辐照大鼠失能效应的脑电观察[J]. 强激光与粒子束, 2010, 22(2): 284-288.
[23] 谢涛嵘, 裴剑, 李芬. 毫米波辐照下大鼠脑电的长程相关性[J]. 强激光与粒子束, 2011, 23(1): 141-145.
[24] 陈超, 李芬, 张杰,等. 高功率毫米波辐照对大鼠血液生化指标的影响[J]. 中国辐射卫生, 2009, 18(4): 392-395.
[25] 张杰, 韩黎军, 齐红星,等. 高功率厘米波辐照黄粉虫幼虫和草坪热效应研究[J]. 强激光与粒子束, 2008, 20(7): 1 137-1 141.