RADIATION PROTECTION BULLETIN ›› 2022, Vol. 42 ›› Issue (6): 9-14.

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DNA Methylation and Its Application in Radiation Protection

Su Lixia, Zhan Jingming, Gu Xiaona, Xue Xiangming, Wu Baoli   

  1. China Institute for Radiation Protection, Taiyuan, Shanxi 030006
  • Received:2022-03-10 Online:2022-12-20 Published:2023-01-04

Abstract: The changes in DNA methylation and ionising radiation-induced whole genome DNA, DNA methylation in specific gene promoter regions and repeated sequence DNA methylation levels are reviewed. The possible mechanism of changes in DNA methylation patterns induced by ionising radiation are discussed, and the application of DNA methylation in radiation protection is introduced.

Key words: Ionizing radiation, DNA methylation, Mechanism, Radiation protection

CLC Number: 

  • R818