To explore the treatment technique of such radiation injuries as in a major radiological accident in which a victim suffered mild bone marrow radiation sickness combined wiht heavy acute radiation induced skin injury, based on his dose estimation, clinical manifestations and disease treatments. History inquiry in detail, earlier physical dose estimation and biological dose estimation were conducted in conjunction with analyzing the chromosome aberration of peripheral blood lymphocytes. The physical dose was estimated by Monte Carlo method. The systematic laboratory and imaging examination was performed to evaluate the condition.The comprehensive analysis was conducted to determine the diagnosis and treatment plan. During the treatment of patients with radiation injury, we should pay attention to the combination of physiology and psychology. Local application of autologous SVF transplantation and skin transplantation can achieve good results in radioactive skin injuries.

To investigate the radiation resources and frequency in medical institutions in our district, providing a basis for the reasonable formulation of radiation protection strategies. Collect the basic information of all institutions with radiation services (excluding dental clinics) in our district and conduct statistical analysis. There were 54 institutions with radiation services (excluding dental clinics) in our district, with 12 667 staff members and 484 radiation staff members,and 231 pieces of radiation equipment; Personal protective equipment and auxiliary protective equipment totaling 945 items, with insufficient provision of lead hanging protective screens/lead protective curtains, which is 50%; The frequency of X-ray diagnosis was 1 234.1 per 1 000 population, and the frequency of conventional X-ray diagnosis was 488.7 per 1000 population, the frequency of CT diagnosis was 676.3 per 1 000 population, the frequency of dental photography diagnosis was 53.7 per 1 000 population, the frequency of bone density test was 9.7 per 1000 population, the frequency of mammography diagnosis was 5.8 per 1000 population, the frequency of interventional diagnosis and treatment was 6.0 per 1 000 population, the frequency of radiotherapy was 0.4 per 1 000 population, the frequency of nuclear medicine diagnosis was 6.1 per 1 000 population, the frequency of nuclear medicine treatment was 0.3 per 1 000 population; CT diagnosis accounts for the highest proportion in X-ray diagnosis(54.8%);the per 1 000 population frequency of CT diagnosis obviously higher than conventional X-ray diagnosis,this is completely different from other cities. Grasped the basic situation and usage frequency of radioactive treatment institutions in the jurisdiction,CT diagnosis has a significant weightage, it is necessary to recognize the rationality of CT examinations, and strive to minimize the radiation dose received by examinees.

A census-based survey was conducted on radioactive medical institutions(excluding dental clinics) in Jinan City. The data on radioactive medical equipment resources and the frequency of radioactive medical applications was collected from 12 districts and counties in Jinan, and equity of equipment resource based on population and geographical distribution was analyzed by Lorenz curve and Gini coefficient.In the population distribution, radioactive medical institutions were in an absolutely fair state,and radioactive medical equipment was in a relatively fair state.In terms of geography,radioactive medical institutions demonstrated significant disparity, with radioactive medical equipment showing extreme disparity. The resource allocation of radioactive medical equipment and the frequency of radioactive medical applications in Jinan City exhibit substantial regional disparities. It is recommended to optimize regional distribution and enhance overall equity in resource allocation.

To screen the differentially expression genes (DEGs) in peripheral blood lymphocytes and verify the dose-response and temporal response, and to explore the feasibility of DEGs as a radiation biological dosimeter. Human peripheral blood samples from 3 adult volunteers were exposed to X-rays at doses of 0, 0.1, 0.2, 0.5, 1, 2 and 4 Gy. RNA-sequencing and bioinformatics analyses were performed. DEGs were screened out under the conditions of log₂|Fold Change| ≥2,P<0.05. The cluster heat map analysis, Gene Ontology (GO) term enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis were applied for the identification of DEGs. Among these DEGs, EDA2R, ACER2, CD70, ACTA2, MGAT3, MAMDC4 were verified for the dose response and temporal response to ionizing radiation by qRT-PCR. We identified 37 DEGs at doses of 0, 0.1, 0.2, 0.5, 1, 2 and 4 Gy at 8 h post-irradiation. The GO analysis of DEGs was mainly enriched in cellular process, single-organism process, cell, cell part, binding. KEGG pathway analysis highlighted the significance of cell growth and death. Doses of 0, 0.1, 0.2, 0.5, 1, 2 and 4 Gy led to a dose-dependent increase in the mRNA levels of EDA2R, ACER2, CD70, ACTA2. The mRNA expression of ACTA2 after 2 Gy X-ray irradiation was shown to be elevated in a time-dependent manner, revealed a temporal response to ionizing radiation. A dose-dependent increase in expression of EDA2R, ACER2, CD70, ACTA2,and a time-dependent increase in ACTA2 in human peripheral lymphocyte samples were demonstrated, indicating the potential of these genes to be biomarkers of human radiation exposure.

In recent years, with the vigorous development of emerging technologies such as unmanned aerial vehicles (UAVs) and small autonomous underwater vehicles (AUVs), their application scope has become increasingly extensive, and there is a risk of their improper use as a means of illegal intrusion. As important and sensitive facilities, nuclear power plants may currently face multi-dimensional and three-dimensional intrusion risks from the low-altitude, maritime and underwater domains. This paper analyzes the potential risks of new types of threats, identifies the relevant typical scenarios and key performance indicators for prevention, and conducts a comparative evaluation of various detection and countermeasure methods. Based on this analysis, a "Three-Layer and Three-Domain" three-dimensional security system architecture and a phased deployment path are proposed, aiming to provide a reference with quantitative indicators and engineering paths for nuclear power plants to construct a composite and three-dimensional defense system.

Wound contamination by radionuclide is a common scenario in nuclear and radiation accidents, and its medical management constitutes a crucial aspect of nuclear emergency medical rescue. Radionuclide wound contamination can cause various hazards such as internal radiation injury, risk of stochastic effects, chemical toxicity, wound healing disorders, contamination spread and transfer, and increased psychological burden. The US National Council on Radiation Protection and Measurements(NCRP), in collaboration with the International Commission on Radiological Protection(ICRP), has developed a biokinetic model for wounds contaminated with radionuclides. This model categorizes the radionuclides at the wound site into five states based on their physicochemical properties and summarizes the dynamic laws of retention, absorption, accumulation, and excretion of soluble and insoluble nuclides in the wound. In light of the actual application scenarios of nuclear emergency medical rescue, this paper further sorts out the guiding significance of the above-mentioned biokinetic model in the rescue practice for early medical treatment decisions and decorporation therapy, etc., hoping to provide some reference for colleagues engaged in nuclear emergency medical rescue.

With the widespread global application of nuclear energy and rising geopolitical risks, the potential threat of nuclear and radiological emergencies (NRE) persists. Nuclear radiation exposure can lead to multi-organ and multi-system damage, and traditional symptomatic supportive care and treatment are limited. Stem cells provide revolutionary therapeutic potential for nuclear emergency medical rescue by virtue of their multiple biological functions such as tissue repair, immune regulation and hematopoietic reconstruction. This paper intends to explore the application strategy of stem cell scale expansion technology in nuclear emergency medical rescue.

As a novel form of knowledge organization, knowledge graphs have enhanced the efficiency, accuracy, and intelligence of emergency medical rescue in the nuclear and radiation field. This paper introduces the concept of knowledge graphs, the key technologies for constructing knowledge graphs in the field of nuclear emergency medical rescue, and analyzes their applications in this field, aiming to provide references for further enhancing the application of knowledge graphs in this area.