RADIATION PROTECTION BULLETIN ›› 2023, Vol. 43 ›› Issue (6): 1-5.

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Research Progress on the Application of Biological Samples Collection in Radionuclide Internal-Contamination Dose Monitoring

Guo Shanshan, Liu Liu, Hou Bei, Zhu Lei, Gao Yan   

  1. PLA Rocket Force Characteristic Medical Center,Beijing 100088
  • Received:2023-07-19 Online:2023-12-20 Published:2024-01-22

Abstract: Biological sample collection can be used to monitor the internal radiation dose of radionuclides. Through the collection of urine, feces, nasal secretions, blood and other biological samples, in order to analyze the radioactivity level and know about the retention amount and dynamic change of radionuclides in the body. The method of urine sample collection is convenient and easy to obtain samples and preserve, which is the first choice for measuring the internal exposure level after nuclear accident; Fecal analysis is often used for relatively insoluble forms of radionuclides inhaled in the body; Nasopharyngeal swabs can be used for the detection of radionuclide deposits formed by aerosol particles, which is a rapid method for the detection of internal irradiation α/β particles produced by human body. Different biological sample collection mrthod has advantages and disadvantages in radionuclide internal contamination dose detection. This review paper aims to provide new ideas for the application of biological sample collection in clinical practice and the study of internal irradiation dose.

Key words: Biological samples, Collection, Radionuclides, Internal contamination, Radioactivity monitoring

CLC Number: 

  • TL73