放射性骨丢失机制与防护研究进展

Abstract

Abstract: Radiotherapy may cause radiation-induced bone damagein the irradiated area, including bone loss, osteoporosis and even pathological fracture. The main causefor bone loss of this type is that ionizing radiation can promotebone resorption of osteoclasts and inhibit genesis of osteoblasts. On account of specific mechanisms involved, and theresponses of bone tissue cells to different radiation doses, corresponding treatment and protective measures should be taken. Advances in research of radiation-induced bone loss and its protection at both animal and cell levels was reviewed accordingly.

Key words: Ionizing radiation, Bone loss, Bone tissue cells, Radiation protection

CLC Number:

R852.7

Qiu Xinyu, Yan Yujie, Xi Kedi, Zhang Kunlan, Hu Wentao, Zhang Jian. Research Progress on Radiation-induced Bone Loss and its Protection[J].RADIATION PROTECTION BULLETIN, 2019, 39(2): 23-33.

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Research Progress on Radiation-induced Bone Loss and its Protection

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