RADIATION PROTECTION ›› 2023, Vol. 43 ›› Issue (4): 366-371.

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Evaluation of the application value of chromosome aberration and micro-nucleus analysis in occupational health surveillance of radiation workers

HAN Lin1, ZHAO Fengling1, LIU Yulong2, LYU Yumin1   

  1. 1. The Third People’s Hospital of Henan Province (Henan Occupational Disease Hospital), Henan Key Laboratory of Medicine on Radiobiology and Epidemiology, Zhengzhou 450052;
    2. Second Affiliated Hospital of Soochou University, Jiangsu Suzhou 215004
  • Received:2022-08-08 Online:2023-07-20 Published:2023-07-25

Abstract: Application of chromosome aberration and micro-nucleus in peripheral blood lymphocyte as radio-sensitive biological indicators to biodosimetry was widely recognized by the international academia. Nevertheless some problems on the application value of the indicators are still worth discussing in occupational health surveillance of radiation workers. In this paper, based on the formation mechanism of chromosome aberration and micro-nucleus, the signification and practical value of the two indicators were explored in occupational medical examination of radiation workers, in order to provide discussion and a reference for the counterparts.

Key words: radiation workers, occupational health surveillance, chromosome aberration, micro-nucleus

CLC Number: 

  • TL75