Abstract: In order to optimize the application of mammography in breast cancer screening, we retrospectively analyzed 132 patients with 139 lesions who underwent mammography and breast color doppler ultrasonography in our hospital, and obtained pathological results(CC), medial lateral oblique view (MLO), breast compression thickness, breast density and the average glandular dose (AGD) received by the subjects, and the detection of lesions in two positions.The results showed that: (1) Both breast compression thickness and breast density were independent influencing factors of AGD, and were positively correlated; and the influence of breast compression thickness on AGD was greater than that of breast density. (2) The exposure parameters tube voltage and tube current tended to increase with the increase of breast compression thickness, resulting in the increase of AGD. (3) No specific pattern was found in the compression thickness and AGD of CC and MLO in the same breast, but the mean ± standard deviation at CC position was (2.49±0.84) which is greater than that of MLO position (2.27±0.81), and MLO was more prone to display lesions than CC. MLO combined with breast color Doppler ultrasound examination has great advantages, which not only ensures the need for diagnosis, but also reduces the AGD value of the subject. Moreover, the greater the thickness of breast compression and the density of the subject, the more the AGD decreases.

Key words: mammography, average glandular dose, breast compression thickness, breast cancer screening