活性氧与放射性皮肤损伤的研究进展

Abstract

Abstract: When the skin is irradiated by radioactive sources, the decomposition of water is the first process to produce reactive oxygen species (ROS), and then the respiratory chain and inflammatory process also produce a large number of ROS. As a signal molecule, ROS plays an irreplaceable role in regulating physiological and biochemical processes. In this paper, the changes of ROS by radiation-induced skin injury, the mechanism of ROS intervention and the regulation of ROS elimination were reviewed in order to link the metabolism of ROS with the physiological and pathological reaction of radiation injury, so as to provide reference for related research and clinical treatment.

Key words: radiation-induced skin injury, reactive oxygen species, autophagy, apoptosis, inflammation

CLC Number:

R818.7

CAI Weichao, CAO Weihong. Research progress of reactive oxygen species and radiation-induced skin injury[J].RADIATION PROTECTION, 2022, 42(2): 111-118.

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Research progress of reactive oxygen species and radiation-induced skin injury

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