指甲电子顺磁共振(EPR)波谱解析的数学模拟研究

Abstract

Abstract: The objective of this study is to explore the decomposition method of electron paramagnetic resonance (EPR) spectra of fingernails after water treatment, and complete dose estimation using nails as biomaterials. Using C++ to write code, visual studio 2019 Community Edition as the integrated development environment (IDE), under the platform of windows10, the effective information extraction, fitting, simulation, normalization, dose regression of electron paramagnetic resonance spectroscopy were carried out. The results showed that the residual spectra of the three groups of individual samples(RIS2+RIS5,1-10 Gy exposure)are close to a straight line, the R² of dose regression curve is greater than 0.9, and the fitting error is less than 1 Gy. For the 10 person mixed group(RIS2+RIS5,1-10 Gy exposure), R² was close to 0.9 (0.89), and the fitting error was about 1.1 Gy, while for the RIS5 fitting group, R² was greater than 0.9, and the fitting error was 4.78 Gy (5-55 Gy exposure). By fitting the EPR spectrum of fingernails with mathematical simulation, we can separate the overlapped signals into RIS spectrum, which can reduce the influence of background signal on dose reconstruction to a certain extent.

Key words: nail, EPR, dose estimation, spectrum analysis

CLC Number:

TB98

YAN Changxin, LIU Yulian, JIAO Ling, ZHANG Wenyi. Study on mathematical simulation of electron paramagnetic resonance (EPR) spectrum analysis of nail[J].RADIATION PROTECTION, 2021, 41(3): 210-217.

References

[1] Flood A B, Nicolalde R J, Demidenko E, et al. A framework for comparative evaluation of dosimetric methods to triage a large population following a radiological event[J]. Radiat Meas, 2011, 46(9): 916-922.
[2] 裘祖文. 电子自旋共振波谱[M]. 北京:科学出版社, 1980.
[3] 赵保路. 电子自旋共振技术在生物和医学中的应用[M]. 合肥:中国科学技术大学出版社, 2009.
[4] Marciniak A, Ciesielski B. EPR dosimetry in nails—A review[J]. Applied Spectroscopy Reviews, 2016, 51(1): 73-92.
[5] Rice R H, Xia Y, Alvarado R J, et al. Proteomic analysis of human nail plate[J]. J Proteome Res, 2010, 9(12): 6752-6758.
[6] Reyes R A, Trompier F, Romanyukha A. Study of the stability of EPR signals after irradiation of fingernail samples[J]. Health Physics, 2012, 103(2): 175-180.
[7] Chandra H, Symons M C. Sulphur radicals formed by cutting alpha-keratin[J]. Nature, 1987, 328(6133): 833-834.
[8] Romanyukha A, Trompier F, Leblanc B, et al. EPR dosimetry in chemically treated fingernails[J]. Radiation measurements, 2007, 42: 1110-1113.
[9] 王宏力, 张慧芳, 任越, 等. 指甲机械诱导电子顺磁共振信号消除方法的比较[J].辐射防护通讯, 2016, 36(01): 37-39.
WANG Hongli,ZHANG Huifang,REN Yue, et al. The comparison of elimination methods for MIS in nails[J].Radiation Protection Bulletin, 2016, 36(01): 37-39.
[10] 赵徵鑫, 张腾达, 张文艺, 等. 指甲电子顺磁共振受照剂量重建误差来源分析[J],辐射研究与辐射工艺学报, 2016,(7): 124-127.
ZHAO Zhixin, ZHANG Tengda, ZHANG Wenyi, et al.Analysis of the error sources of the radiation dose reconstruction in the fingernail;electron paramagnetic resonance[J].Journal of Radiation Research and Radiation Processing, 2016,(7): 124-127.
[11] 张腾达, 王萧, 赵徵鑫, 等. 指甲电子顺磁共振定量检测理论、注意事项及方法进展[J].辐射研究与辐射工艺学报,2015, 33(4): 1-6.
ZHANG Tengda,WANG Xiao,ZHAO Zhixin, et al. Theory, matters needing attention and recent progress of fingernail electron paramagnetic resonance quantitative measurements[J].Journal of Radiation Research and Radiation Processing,2015, 33(4): 1-6.
[12] Hunter J D. Matplotlib: A 2D graphics environment[J]. Computing in Science & Engineering, 2007, 9(3): 90-95.
[13] Romanyukha A, Reyes R A, Trompier F, et al. Fingernail dosimetry: current status and perspectives[J]. Health Phys, 2010, 98(2): 296-300.
[14] Trompier F, Queinnec F, Bey E, et al. EPR retrospective dosimetry with fingernails: report on first application cases[J]. Health Phys, 2014, 106(6): 798-805.
[15] Romanyukha A, Trompier F, Reyes R A, et al. Electron paramagnetic resonance radiation dose assessment in fingernails of the victim exposed to high dose as result of an accident[J]. Radiat Environ Biophys, 2014, 53(4): 755-62.
[16] Reyes R A, Romanyukha A, Olsen C, et al. Electron paramagnetic resonance in irradiated fingernails: variability of dose dependence and possibilities of initial dose assessment[J]. Radiat Environ Biophys, 2009, 48(3): 295-310.
[17] Trompier F, Romanyukha A, Reyes R, et al. State of the art in nail dosimetry: free radicals identification and reaction mechanisms[J]. Radiat Environ Biophys, 2014, 53(2): 291-303.
[18] Tipikin D S, Swarts S G, Sidabras J W, et al. Possible nature of the radiation-induced signal in nails:high-field EPR, confirming chemical synthesis,and quantum chemical calculations[J]. Radiation Protection Dosimetry, 2016, 172(1-3): 112-120.
[19] Trompier F, Romanyukha A, Kornak L, et al. Electron paramagnetic resonance radiation dosimetry in fingernails[J]. Radiation Measurements, 2009, 44(1): 6-10.

Study on mathematical simulation of electron paramagnetic resonance (EPR) spectrum analysis of nail

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