基于蒙特卡罗数学模型评价不同螺距冠状动脉CCTA受检者辐射剂量的特点与验证

Abstract

Abstract: The distribution characteristics of radiation dose of Coronary Computed Tomography Angiography (CCTA) with high-pitch and standard-pitch is studied using Monte Carlo simulation. The data from 61 patients subjected to high-pitch CCTA using the dual source CT scanner were collected and divided into 3 groups according to the BMI classification for Asians recommended by WHO: normal group (12 cases), overweight group (41 cases) and obese group (8 cases). Organ dose and effective dose (E) of the three groups with high-pitch and standard-pitch CCTA were calculated using Monte Carlo software. In high-pitch mode, the effective dose values calculated by Monte Carlo software were compared with the direct data readings from the CT equipment. The results showed that the organ dose of high-pitch CCTA calculated by the Monte Carlo software was about 70% lower than that of standard-pitch CCTA on the dual source spiral CT. The most significant reductions in organ doses were found for heart and thymus, which have decreased by about 80%. For all the 3 groups, the effective doses of high-pitch CCTA were significantly lower than those of the standard-pitch CCTA (p<0.05), and the most obvious reduction in E was found in patients of the normal group subjected to the high-pitch CCTA. In high-pitch mode, deviation in E between the Monte Carlo simulation and the reading of the CT device was less than 50%. This suggested that, as a new clinical calculation method for radiation dose, Monte Carlo simulation can be used for prediction or retrospective analysis of the distribution of organ dose and E in CCTA. It is also indicated that the chest organ dose and effective dose can be significantly reduced with the high-pitch CCTA, and this will subsequently decrease the radiation risk, especially for the subjects of smaller BMI (such as children). This study has a potential for practical applications in development of low dose CT technology.

Key words: Coronary Computed Tomography Angiography (CCTA), dual source computed tomography, computed tomography, mathematical model, radiation dose

CLC Number:

TL72

Liu Xiao, Zeng Yongming, Yu Rengqiang, Wang Jie, Sun Jingkun. Estimation and validation of radiation dose to patients subjected to high-pitch and standard-pitch CCTA using Monte Carlo software[J].RADIATION PROTECTION, 2017, 37(2): 131-137.

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Estimation and validation of radiation dose to patients subjected to high-pitch and standard-pitch CCTA using Monte Carlo software

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