Effect of software-based scatter correction on radiation dose in mammography
CHEN Lu, GAO Zhizhen
RADIATION PROTECTION BULLETIN. 2024, 44(4):
1-6.
Abstract
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Purpose: This study investigated the relationship between average glandular dose and compressed thickness and gland type in the software-based Progressive Reconstruction Intelligently Minimizing Exposure (PRIME) model. The extent of average glandular dose reduction(AGD) in PRIME mode is compared to full field digital mammography (FFDM) and influencing factors. Materials and Methods: 515 female patients who underwent PRIME mode and FFDM on the left and right breast under the same compressed thickness were collected respectively. A total of 1 030 breast craniocaudal view images and 1 030 breast mediolateral oblique view images were analyzed. Results: Breast compressed thickness was positively and strongly correlated with AGDPRIME (r=0.698, P<0.001), gland type and compressed force were positively and weakly correlated with AGDPRIME (r=0.227,r=0.228,P<0.001), and age was negatively correlated with AGDPRIME (r=-0.327,P<0.001 0 .Breast compressed thickness, gland type, compressed force and age were independent factors for AGDPRIME (Bcompressed thickness=0.025, Bgland type=0.238, Bcompressed force=0.001, Bage=-0.007, P<0.001). The standardized coefficients of compressed thickness, gland type, compressed force and age were 0.735, 0.229, 0.106 and -0.244, respectively. The effect of compressed thickness on AGDPRIME was greater than that of gland type. Breast compressed thickness and age were negatively correlated with △AGD (AGDFFDM minus AGDPRIME) (r=-0.565,r=-0.127,P<0.001), while gland type was positively correlated with △AGD (r=0.159,P<0.001). Breast compressed thickness and age were independent factors of △AGD (Bcompressed thickness=-0.011,Bage=-0.002,the standardization coefficients were -0.558 and -0.104, respectively). Breast compressed thickness was negatively correlated with the rate of dose-reduction in PRIME mode, and linear fitting showed a higher dose reduction in thinner breasts. Conclusions: AGDPRIME is positively correlated with breast compressed thickness, gland type and compressed force, and compressed thickness has a greater effect on AGDPRIME. △AGD is negatively correlated with compressed thickness and age, and the effect of PRIME acquisition mode on reducing glandular dose in young patients with small breast compressed thickness is more obvious.