细胞衰老在放射损伤发生发展中的研究进展

Abstract

Abstract: Radiation injury is a common complication of radiotherapy for cancer patients. Radiation injury has a relative high incidence and is difficult to prevent and to be treated, which may seriously affects the life quality of patients. Cell senescence is a state in which the cell cycle is stagnated, and radiation therapy usually makes cells enter a state of senescence, which facilitates the removal of tumor cells in the body while may also causing damage to normal cells. With the progress of research, the role of ionizing radiation-induced cell senescence in radiation injury has received more and more attention, and the research progress of cell senescence in radiation injury is reviewed in this paper.

Key words: cell senescence, ionizing radiation, radiation injury

CLC Number:

R818

NIU Xiaofeng, YANG Siyu, DENG Lijuan, REN Zheng, BI Chengliu, YANG Jun. Research progress of cell senescence in the occurrence and development of radiation injury[J].RADIATION PROTECTION BULLETIN, 2024, 44(6): 1-9.

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Research progress of cell senescence in the occurrence and development of radiation injury

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