基因组不稳定性与辐射致癌

Abstract

Abstract: Ionizing radiation induces genomic stability, which is transmitted over many generations after irradiation. Since induced genomic instability accumulates gene mutations, it has been thought to playa role in radiation-induced carcinogenesis. Understanding the mechanism of genomic instability will provide unique opportunities to identify new diagnosis andtherapeutic targets. This review focuses on recent discoveries on the mechanismsgoverning the formation of genomic instability.

Key words: Genomic instability, Radiation-induced carcinogenesis, Mechanism

CLC Number:

Q691

Yuan Yayi, Zuo Yahui. Mechanisms and Role of Genomic Instability in Radiation-induced Carcinogenesis[J].RADIATION PROTECTION BULLETIN, 2014, 34(2): 24-27.

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Mechanisms and Role of Genomic Instability in Radiation-induced Carcinogenesis

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