膳食补充剂在低剂量辐射防护中的应用

摘要/Abstract

摘要： 本文分析了维生素类和矿物质、中药提取物、多糖、藻类、蜂胶等膳食补充剂对外/内照射损伤防护的文献报道,这些膳食补充剂不仅具有辐射防护作用,而且毒副作用小,可为膳食补充剂的配伍提供研究依据。

Abstract: Nuclear technology has been widely used, and Dietary Supplementa have attracted more and more attention. It is necessary to study the protective effects of safe, effective and the low side effects of dietary supplements on the body. By analyzing the literature reports on the protection of vitamins, minerals, traditional Chinese medicine extracts, polysaccharides, algae and other substances from external/internal radiation damage, this paper provides rich research content for the compatibility of dietary supplements, to protect the health of practitioners.

Key words: Radiation protection, Low dose, Dietary supplement

中图分类号:

R142⁺.4

郭剑平, 张亚娟, 袁慧, 李建华, 郭婷婷, 王婧荃. 膳食补充剂在低剂量辐射防护中的应用[J]. 辐射防护通讯, 2022, 42(6): 15-20.

Guo Jianping, Zhang Yajuan, Yuan Hui, Li Jianhua, Guo Tingting, Wang Jingquan. Application of Dietary Supplements in the Protection of Low Dose Radiation[J]. RADIATION PROTECTION BULLETIN, 2022, 42(6): 15-20.

参考文献

[1] Austin K G,Mclellan T M,Farina E K,et al.Soldier use of dietary supplements,including protein andbody building supplements,in a combat zone is differentthan use in garrison[J].Applied Physiology,Nutrition,and Metabolism,2016,41(1):867-868.
[2] 兰洁,王瑾, 王森,等.国际保健品管理的比较研究(上)[J].亚太传统医药,2008,4(7):3-6.
[3] 田明,冯军,孙璐,等.美国膳食补充剂管理研究及对中国的启示[J].中国食物与营养, 2020,26(12):5-8.
[4] 李春阳.保健食品与膳食补充剂的商标保护[J].商标实务,1999,33(1):16-17.
[5] Klosky J L.Briefreport: evaluation of an interactive intervention de-signed to reduce pediatric distress during radiation therapy proce-dures[J].J Pediatr Psychol,2004,29(8):621-626.
[6] Tang F R,Loganovsky K.Low dose or low dose rate ionizing radia-tion-induced health effect in the human[J].J Environ Radioact,2018,192: 32-47.
[7] Marazziti D,Baroni S,Catena-Dellosso M,et al.Cognitive,psychological and psychiatric effects of ionizing radiation exposure[J].CurrMed Chem,2012,19(12):1864-1869.
[8] 杨林,张月明,徐臻荣,等.抗坏血酸体外抗肿瘤作用的实验研究[J].中国公共卫生, 1999, 15(10):867.
[9] 马爱国,Duthie S J,Ross M A,等.维生素E、C和β-胡萝卜素对DNA损伤的影响[J].中华预防医学杂志,1998,33(1):163.
[10] Harapanhalli R S,Yaghmai V,Giuliani D,et al.Antioxidanteffectsofvitam in Cinmice followeing X-irradiation[J].Res Commun Mol Pathol Pharmacol,1996,94(3):271-287.
[11] 傅春玲,江伟威,张萍,等.维生素C抗辐射损伤作用研究[J].苏州医学院学报,2000,20(9):793-795.
[12] 王小慧,周正宇,李冰燕,等.维生素D对⁶⁰Co辐射损伤小鼠的保护作用[J].辐射研究与辐射工艺学报,2008,26(2):122-124.
[13] Eberlein-Konig B,Fesq H,Abeck D,et al.Systemicvitamin Candvitamin Edonot prevent photo provocation test reactionsinpo lymorphous lighteruption[J].Photodermatol Photoimmunol Photomed,2000,16(2):50－52.
[14] 梁欣,海春旭,秦绪军,等.Vit.C,E对⁶⁰Co γ线照射家兔血清和肝脏SOD和MDA影响[J].第四军医大学学报,2002,23(11):1019-1022.
[15] 郭英,冯彪,隋志仁.硒对辐射所致过氧化脂质含量及谷胱甘肽过氧化物酶活性的影响[J].营养学报,1992,14(3):251-253.
[16] Sorokinaa S S, Zaichkinaa S I, Rozanovaa O M,et al.The combined effects of dietary supplements and low dose rate high LET radiation on mice in vivo[J].Biophysics, 2016,61(1): 144-148.
[17] Zuo X Y, Chen Q, Li H W,et al.Effects of chahuangjing on decorporation and radiation protection against tritiated water[J].Dose-Response,2018,16(4):1-6.
[18] 关素珍,德小明,庞克华,等.枸杞多糖对脊髓神经细胞辐射损伤后的保护作用研究[J].癌变·畸变·突变,2019,31(1):45-48.
[19] 黄晓舞,白林,温利青,等.青稞多糖对辐射损伤小鼠免疫功能的影响[J].解放军药学学报,2009,25(6):479-481.
[20] 许小敏,卢志伟,王磊,等.当归多糖防护X线对大鼠骨髓及脾脏损伤的研究[J].中国药理学通报,2017,33(11):1553-1558.
[21] 于涛,王蕾,纪建达,等.两种海洋生物多糖对⁶⁰Co辐射损伤小鼠保护作用的研究[J].辐射防护,2019,39(3):242-248.
[22] Eveliina R,Jolanta K,Warcho,et al.Heavy metals a orption by novel EDTA-modified chitosan-silica hybrid materials[J].Journal of Colloid and Interface Science,2011,358: 261-267.
[23] 翟小刚,许玉杰,刘敏,等.壳聚糖衍生物纳米粒子的制备及对体内放射性锶的促排作用[J].中国辐射卫生,2012,21(2):129-131.
[24] 姚亦天,吴梓茹,欧阳杰,等.羧甲基壳聚糖对铀的促排及肠道菌群的影响[J].湿法冶金,2020,39(1):80-84.
[25] 胡丹飞,毕梦,袁海浪,等.新型促排剂WSC-DTPA纳米粒对内污染铀的促排和防护作用[J].辐射研究与辐射工艺学报,2013,31(4):040202(1-6).
[26] 敖翩,赵歆,玉洪荣,等. 海带多糖干预对放射性脑损伤模型小鼠血脑屏障的保护 [J]. 中国组织工程研究,2022,26(20):3158-3163.
[27] 张哲,张筠.海带中的生理活性多糖[J].食品科技,1999,(3):52-53.
[28] 阮继红,庞启深,郭宝江,等.螺旋藻抗辐射的研究[J].遗传,1988,10(2):27-30.
[29] 梁明至,冉新泽,郭朝华,等.钝顶螺旋藻多糖对辐射所致小鼠造血功能抑制的对抗影响[J].重庆医学,2003,32(3):293-295.
[30] 李思雨,刘红全,孙寒,等.小球藻胞内多糖提取纯化及其抗氧化活性[J].食品工业科技,2022,43(15):209-219.
[31] Kazuma O, Tadahisa F, Jaegab H,et al.Evaluation of chlorella as a decorporation agent to enhance the elimination of radioactive strontium from body[J].PLOS ONE,2016. DOI:10.1371/journal.pone.0148080:1-10.
[32] 郭月凤.蜂胶防治辐射损伤的应用潜势[J].中国职业医学,2004,31(5):61-62.
[33] 丁建松,聂继华,童建.蜂胶对氡及其子体吸入致大鼠损伤的防护作用研究[J].辐射研究与辐射工艺学报,2006,24(5):317-320.
[34] Socol Y, Dobrzyński L, Doss M, et al. Commentary: ethical issues of current health-protection policies on low-dose ionizing radiation [J]. Dose Response, 2013,12(2): 342-348.
[35] 闵锐.低剂量 /低剂量率电离辐射生物效应[J].辐射研究与辐射工艺学报,2014,32(6):060101(1-9).
[36] 杨红丽,杨晓文.职业接触低剂量电离辐射对健康影响的探讨[J].中国药物与临床,2017,17(3):351-352.
[37] 高月.低剂量辐射药物防护研究概况[C].第六届海峡两岸毒理学研讨会论文集,2011:59-60.