贫铀对啮齿类动物和人类生殖毒性研究进展

辐射防护通讯 ›› 2020, Vol. 40 ›› Issue (1): 38-42.

贫铀对啮齿类动物和人类生殖毒性研究进展

潘泽轩, 尹晶晶, 高洁, 刘欢, 李建国

中国辐射防护研究院放射医学与环境医学研究所;药物毒理与放射损伤药物山西省重点实验室,太原,030006

收稿日期:2020-01-20 发布日期:2020-07-10
通讯作者: 李建国,ljg2547@163.com
作者简介:潘泽轩(1992—),男,2016年毕业于吉林大学放射医学专业,学士;现为中国辐射防护研究院放射医学专业研究生。

Advances in Studies on Reproductive Toxicity of Depleted Uranium to Rodents and Humans

Pan Zexuan, Yin Jingjing, Gao Jie, Liu Huan, Li Jianguo

China Institute for Radiation Protection, Key Laboratory of Drug Toxicology and Drug for Radiation Injury, Taiyuan, Shanxi, 030006

Received:2020-01-20 Published:2020-07-10

摘要/Abstract

摘要： 贫铀广泛应用,以多种形态存在于自然界中,其潜在的毒性威胁不容忽视。本文介绍了贫铀对啮齿类动物和人类生殖毒性的研究进展,主要包括对生殖器官损伤的严重程度、发展趋势、遗传损伤、作用方式、相关机制和研究方法等。研究表明,贫铀暴露在多个层面损伤啮齿类动物和人的生殖和遗传功能。

关键词: 贫铀, 生殖系统, 毒性研究

Abstract: The research progress of the reproductive toxicity of depleted uranium to rodents and humans, is reviewed, including the severity of reproductive organ damage, the development trend, the genetic damage, action modes, related mechanisms and research methods. Studies have shown that depleted uranium exposure damages the reproductive and genetic functions of rodents and humans at multiple levels.

Key words: Depleted uranium, Reproductive system, Toxicity studies

中图分类号:

X591

潘泽轩, 尹晶晶, 高洁, 刘欢, 李建国. 贫铀对啮齿类动物和人类生殖毒性研究进展[J]. 辐射防护通讯, 2020, 40(1): 38-42.

Pan Zexuan, Yin Jingjing, Gao Jie, Liu Huan, Li Jianguo. Advances in Studies on Reproductive Toxicity of Depleted Uranium to Rodents and Humans[J]. RADIATION PROTECTION BULLETIN, 2020, 40(1): 38-42.

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