γ射线对Beagle犬肠道组织及粪便菌群的影响

辐射防护通讯 ›› 2021, Vol. 41 ›› Issue (5): 19-23.

γ射线对Beagle犬肠道组织及粪便菌群的影响

许文黎, 李曙芳, 王新钢, 王远飞, 王永丽, 胡波, 李建国

中国辐射防护研究院GLP中心; 山西太原,030006

收稿日期:2021-08-08 出版日期:2021-10-20 发布日期:2022-03-31
通讯作者: 李建国,E-mail:ljg2547@163.com
作者简介:许文黎(1986—),女,2005年毕业于哈尔滨医科大学预防医学专业,本科;2013年毕业于中国辐射防护研究院放射医学专业,硕士。副研究员,主要从事药物临床前安全性评价与辐射防护。

Effects of Gamma Rays on Intestinal Tissue and Fecal Flora of Beagles

Xu Wenli, Li Shufang, Wang Xingang, Wang Yuanfei, Wang Yongli, Hu Bo, Li Jianguo

GLP Centre,China Institute for Radiation Protection,Taiyuan,Shanxi 030006

Received:2021-08-08 Online:2021-10-20 Published:2022-03-31

摘要/Abstract

摘要： 采用16srDNA技术,分析⁶⁰Co γ射线不同剂量全身照射对Beagle犬的肠道组织及粪便菌群的影响。结果表明,不同剂量的照射均能导致Beagle犬粪便微生物菌群的结构发生改变,促进或加重肠道损伤。

关键词: γ射线, 比格犬, 肠道损伤

Abstract: Using 16srDNA technique,the dose effect of whole body exposure to ⁶⁰Coγ-rays on the intestinal tissue and faecal flora of Beagles was analysed. The results showed that different doses of ⁶⁰Co could change the structure of fecal microflora,and promote or aggravate intestinal damage,of Beagles.

Key words: Gamma rays, Beagle, Intestinal damage

中图分类号:

R818.03

许文黎, 李曙芳, 王新钢, 王远飞, 王永丽, 胡波, 李建国. γ射线对Beagle犬肠道组织及粪便菌群的影响[J]. 辐射防护通讯, 2021, 41(5): 19-23.

Xu Wenli, Li Shufang, Wang Xingang, Wang Yuanfei, Wang Yongli, Hu Bo, Li Jianguo. Effects of Gamma Rays on Intestinal Tissue and Fecal Flora of Beagles[J]. RADIATION PROTECTION BULLETIN, 2021, 41(5): 19-23.

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